000 01711 a2200457 4500
005 20250514000530.0
264 0 _c20010719
008 200107s 0 0 eng d
022 _a1078-0432
040 _aNLM
_beng
_cNLM
100 1 _avan Kuilenburg, A B
245 0 0 _aLethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.
_h[electronic resource]
260 _bClinical cancer research : an official journal of the American Association for Cancer Research
_cMay 2001
300 _a1149-53 p.
_bdigital
500 _aPublication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAntimetabolites, Antineoplastic
_xmetabolism
650 0 4 _aDihydrouracil Dehydrogenase (NADP)
650 0 4 _aExons
_xgenetics
650 0 4 _aFatal Outcome
650 0 4 _aFemale
650 0 4 _aFibroblasts
_xenzymology
650 0 4 _aFluorouracil
_xmetabolism
650 0 4 _aGene Frequency
650 0 4 _aHumans
650 0 4 _aLeukocytes, Mononuclear
_xenzymology
650 0 4 _aMutation
650 0 4 _aOxidoreductases
_xdeficiency
650 0 4 _aPolymorphism, Restriction Fragment Length
650 0 4 _aThymine
_xblood
650 0 4 _aUracil
_xblood
700 1 _aMuller, E W
700 1 _aHaasjes, J
700 1 _aMeinsma, R
700 1 _aZoetekouw, L
700 1 _aWaterham, H R
700 1 _aBaas, F
700 1 _aRichel, D J
700 1 _avan Gennip, A H
773 0 _tClinical cancer research : an official journal of the American Association for Cancer Research
_gvol. 7
_gno. 5
_gp. 1149-53
999 _c11283421
_d11283421