000			01978 a2200553 4500
005			20250513235748.0
264		0	_c20010531
008			200105s 0 0 eng d
022			_a1061-4036
024	7		_a10.1038/ng0501-29 _2doi
040			_aNLM _beng _cNLM
100	1		_aYoshikawa, H
245	0	0	_aSOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. _h[electronic resource]
260			_bNature genetics _cMay 2001
300			_a29-35 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAntineoplastic Agents _xtherapeutic use
650	0	4	_aCarcinoma, Hepatocellular _xgenetics
650	0	4	_aCarrier Proteins _xgenetics
650	0	4	_aCpG Islands
650	0	4	_aDNA Methylation
650	0	4	_aDNA-Binding Proteins _xmetabolism
650	0	4	_aGene Silencing
650	0	4	_aGenes, Tumor Suppressor
650	0	4	_aGenetic Therapy
650	0	4	_aHumans
650	0	4	_aIntracellular Signaling Peptides and Proteins
650	0	4	_aJanus Kinase 2
650	0	4	_aLiver Neoplasms _xgenetics
650	0	4	_aMolecular Sequence Data
650	0	4	_aProtein-Tyrosine Kinases _xantagonists & inhibitors
650	0	4	_aProto-Oncogene Proteins
650	0	4	_aRepressor Proteins
650	0	4	_aSTAT3 Transcription Factor
650	0	4	_aSignal Transduction
650	0	4	_aSuppressor of Cytokine Signaling 1 Protein
650	0	4	_aSuppressor of Cytokine Signaling Proteins
650	0	4	_aTrans-Activators _xmetabolism
650	0	4	_aTyrphostins _xtherapeutic use
700	1		_aMatsubara, K
700	1		_aQian, G S
700	1		_aJackson, P
700	1		_aGroopman, J D
700	1		_aManning, J E
700	1		_aHarris, C C
700	1		_aHerman, J G
773	0		_tNature genetics _gvol. 28 _gno. 1 _gp. 29-35
856	4	0	_uhttps://doi.org/10.1038/ng0501-29 _zAvailable from publisher's website
999			_c11260209 _d11260209