000			01992 a2200625 4500
005			20250513234721.0
264		0	_c20010607
008			200106s 0 0 eng d
022			_a0036-8075
024	7		_a10.1126/science.1057991 _2doi
040			_aNLM _beng _cNLM
100	1		_aClancy, D J
245	0	0	_aExtension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. _h[electronic resource]
260			_bScience (New York, N.Y.) _cApr 2001
300			_a104-6 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAging _xphysiology
650	0	4	_aAlleles
650	0	4	_aAnimals
650	0	4	_aBody Constitution
650	0	4	_aCarrier Proteins _xgenetics
650	0	4	_aCrosses, Genetic
650	0	4	_aDrosophila Proteins
650	0	4	_aDrosophila melanogaster _xgenetics
650	0	4	_aFemale
650	0	4	_aFertility
650	0	4	_aGenes, Insect
650	0	4	_aHeterozygote
650	0	4	_aHot Temperature
650	0	4	_aInsect Proteins _xgenetics
650	0	4	_aInsulin _xmetabolism
650	0	4	_aInsulin Receptor Substrate Proteins
650	0	4	_aIntracellular Signaling Peptides and Proteins
650	0	4	_aLongevity _xphysiology
650	0	4	_aMale
650	0	4	_aMutation
650	0	4	_aOxidative Stress
650	0	4	_aProtein-Tyrosine Kinases _xgenetics
650	0	4	_aReceptor Protein-Tyrosine Kinases
650	0	4	_aReceptor, Insulin _xmetabolism
650	0	4	_aReproduction
650	0	4	_aSignal Transduction
650	0	4	_aSomatomedins _xmetabolism
650	0	4	_aStarvation
650	0	4	_aSuperoxide Dismutase
700	1		_aGems, D
700	1		_aHarshman, L G
700	1		_aOldham, S
700	1		_aStocker, H
700	1		_aHafen, E
700	1		_aLeevers, S J
700	1		_aPartridge, L
773	0		_tScience (New York, N.Y.) _gvol. 292 _gno. 5514 _gp. 104-6
856	4	0	_uhttps://doi.org/10.1126/science.1057991 _zAvailable from publisher's website
999			_c11228067 _d11228067