| 000 | 01878 a2200517 4500 | ||
|---|---|---|---|
| 005 | 20250513233234.0 | ||
| 264 | 0 | _c20011204 | |
| 008 | 200112s 0 0 eng d | ||
| 022 | _a0027-8424 | ||
| 024 | 7 |
_a10.1073/pnas.051014398 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aXie, W | |
| 245 | 0 | 0 |
_aAn essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cMar 2001 |
||
| 300 |
_a3375-80 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAryl Hydrocarbon Hydroxylases |
| 650 | 0 | 4 |
_aBile Acids and Salts _xmetabolism |
| 650 | 0 | 4 | _aCell Line |
| 650 | 0 | 4 | _aCell Nucleus |
| 650 | 0 | 4 | _aChlorocebus aethiops |
| 650 | 0 | 4 |
_aCholestasis _xmetabolism |
| 650 | 0 | 4 | _aCytochrome P-450 CYP3A |
| 650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xmetabolism |
| 650 | 0 | 4 | _aEnzyme Induction |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLithocholic Acid _xadministration & dosage |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Knockout |
| 650 | 0 | 4 |
_aOxidoreductases, N-Demethylating _xmetabolism |
| 650 | 0 | 4 | _aPregnane X Receptor |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 |
_aReceptors, Cytoplasmic and Nuclear _xphysiology |
| 650 | 0 | 4 |
_aReceptors, Steroid _xphysiology |
| 650 | 0 | 4 | _aSubstrate Specificity |
| 700 | 1 | _aRadominska-Pandya, A | |
| 700 | 1 | _aShi, Y | |
| 700 | 1 | _aSimon, C M | |
| 700 | 1 | _aNelson, M C | |
| 700 | 1 | _aOng, E S | |
| 700 | 1 | _aWaxman, D J | |
| 700 | 1 | _aEvans, R M | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 98 _gno. 6 _gp. 3375-80 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.051014398 _zAvailable from publisher's website |
| 999 |
_c11184961 _d11184961 |
||