000			01675 a2200421 4500
005			20250513231937.0
264		0	_c20010510
008			200105s 0 0 eng d
022			_a0960-894X
024	7		_a10.1016/s0960-894x(00)00641-7 _2doi
040			_aNLM _beng _cNLM
100	1		_aMak, C C
245	0	0	_aDesign, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue. _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cJan 2001
300			_a219-22 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAmino Acid Motifs
650	0	4	_aAminocaproates _xchemistry
650	0	4	_aAntiviral Agents _xchemical synthesis
650	0	4	_aAspartic Acid Endopeptidases _xantagonists & inhibitors
650	0	4	_aCombinatorial Chemistry Techniques
650	0	4	_aDrug Design
650	0	4	_aDrug Resistance
650	0	4	_aHIV Protease Inhibitors _xchemical synthesis
650	0	4	_aImmunodeficiency Virus, Feline _xenzymology
650	0	4	_aInhibitory Concentration 50
650	0	4	_aMolecular Conformation
650	0	4	_aMolecular Mimicry
650	0	4	_aPeptides, Cyclic _xchemical synthesis
650	0	4	_aProtease Inhibitors _xchemical synthesis
650	0	4	_aStructure-Activity Relationship
700	1		_aLe, V D
700	1		_aLin, Y C
700	1		_aElder, J H
700	1		_aWong, C H
773	0		_tBioorganic & medicinal chemistry letters _gvol. 11 _gno. 2 _gp. 219-22
856	4	0	_uhttps://doi.org/10.1016/s0960-894x(00)00641-7 _zAvailable from publisher's website
999			_c11144479 _d11144479