000 | 01748 a2200505 4500 | ||
---|---|---|---|
005 | 20250513230139.0 | ||
264 | 0 | _c20010201 | |
008 | 200102s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm000139k _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aBrown, G R | |
245 | 0 | 0 |
_aA novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cDec 2000 |
||
300 |
_a4964-72 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAnticholesteremic Agents _xchemical synthesis |
650 | 0 | 4 |
_aCholesterol _xbiosynthesis |
650 | 0 | 4 | _aChromatography, High Pressure Liquid |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aIn Vitro Techniques |
650 | 0 | 4 |
_aIntramolecular Transferases _xantagonists & inhibitors |
650 | 0 | 4 |
_aMicrosomes _xdrug effects |
650 | 0 | 4 |
_aPiperazines _xchemical synthesis |
650 | 0 | 4 |
_aPiperidines _xchemical synthesis |
650 | 0 | 4 |
_aPyridines _xchemical synthesis |
650 | 0 | 4 |
_aPyrimidines _xchemical synthesis |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aHollinshead, D M | |
700 | 1 | _aStokes, E S | |
700 | 1 | _aWaterson, D | |
700 | 1 | _aClarke, D S | |
700 | 1 | _aFoubister, A J | |
700 | 1 | _aGlossop, S C | |
700 | 1 | _aMcTaggart, F | |
700 | 1 | _aMirrlees, D J | |
700 | 1 | _aSmith, G J | |
700 | 1 | _aWood, R | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 43 _gno. 26 _gp. 4964-72 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm000139k _zAvailable from publisher's website |
999 |
_c11089991 _d11089991 |