000 01748 a2200505 4500
005 20250513230139.0
264 0 _c20010201
008 200102s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm000139k
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBrown, G R
245 0 0 _aA novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cDec 2000
300 _a4964-72 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aAnticholesteremic Agents
_xchemical synthesis
650 0 4 _aCholesterol
_xbiosynthesis
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aFemale
650 0 4 _aIn Vitro Techniques
650 0 4 _aIntramolecular Transferases
_xantagonists & inhibitors
650 0 4 _aMicrosomes
_xdrug effects
650 0 4 _aPiperazines
_xchemical synthesis
650 0 4 _aPiperidines
_xchemical synthesis
650 0 4 _aPyridines
_xchemical synthesis
650 0 4 _aPyrimidines
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aStructure-Activity Relationship
700 1 _aHollinshead, D M
700 1 _aStokes, E S
700 1 _aWaterson, D
700 1 _aClarke, D S
700 1 _aFoubister, A J
700 1 _aGlossop, S C
700 1 _aMcTaggart, F
700 1 _aMirrlees, D J
700 1 _aSmith, G J
700 1 _aWood, R
773 0 _tJournal of medicinal chemistry
_gvol. 43
_gno. 26
_gp. 4964-72
856 4 0 _uhttps://doi.org/10.1021/jm000139k
_zAvailable from publisher's website
999 _c11089991
_d11089991