000 01799 a2200469 4500
005 20250513225415.0
264 0 _c20010208
008 200102s 0 0 eng d
022 _a0148-396X
040 _aNLM
_beng
_cNLM
100 1 _aBednar, M M
245 0 0 _a16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke.
_h[electronic resource]
260 _bNeurosurgery
_cDec 2000
300 _a1410-8; discussion 1418-9 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aArachidonic Acid
_xmetabolism
650 0 4 _aCell Adhesion
_xdrug effects
650 0 4 _aCell Aggregation
_xdrug effects
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDrug Synergism
650 0 4 _aFibrinolytic Agents
_xpharmacology
650 0 4 _aHumans
650 0 4 _aHydroxyeicosatetraenoic Acids
_xpharmacology
650 0 4 _aIntracranial Embolism and Thrombosis
_xcomplications
650 0 4 _aIntracranial Pressure
_xdrug effects
650 0 4 _aLeukotriene B4
_xantagonists & inhibitors
650 0 4 _aNeutrophils
_xdrug effects
650 0 4 _aRabbits
650 0 4 _aSingle-Blind Method
650 0 4 _aStroke
_xetiology
650 0 4 _aTissue Plasminogen Activator
_xpharmacology
700 1 _aGross, C E
700 1 _aRussell, S R
700 1 _aFuller, S P
700 1 _aAhern, T P
700 1 _aHoward, D B
700 1 _aFalck, J R
700 1 _aReddy, K M
700 1 _aBalazy, M
773 0 _tNeurosurgery
_gvol. 47
_gno. 6
_gp. 1410-8; discussion 1418-9
999 _c11067301
_d11067301