000 02199 a2200589 4500
005 20250513224208.0
264 0 _c20001130
008 200011s 0 0 eng d
022 _a0028-4793
024 7 _a10.1056/NEJM200011233432103
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBombardier, C
245 0 0 _aComparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.
_h[electronic resource]
260 _bThe New England journal of medicine
_c11 2000
300 _a1520-8, 2 p following 1528 p.
_bdigital
500 _aPublication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aArthritis, Rheumatoid
_xdrug therapy
650 0 4 _aCardiovascular Diseases
_xmortality
650 0 4 _aCyclooxygenase 2
650 0 4 _aCyclooxygenase 2 Inhibitors
650 0 4 _aCyclooxygenase Inhibitors
_xtherapeutic use
650 0 4 _aDuodenal Obstruction
_xchemically induced
650 0 4 _aFemale
650 0 4 _aGastric Outlet Obstruction
_xchemically induced
650 0 4 _aGastrointestinal Diseases
_xchemically induced
650 0 4 _aGastrointestinal Hemorrhage
_xchemically induced
650 0 4 _aHumans
650 0 4 _aIsoenzymes
_xantagonists & inhibitors
650 0 4 _aLactones
_xadverse effects
650 0 4 _aMale
650 0 4 _aMembrane Proteins
650 0 4 _aMiddle Aged
650 0 4 _aNaproxen
_xadverse effects
650 0 4 _aPeptic Ulcer
_xchemically induced
650 0 4 _aProportional Hazards Models
650 0 4 _aProstaglandin-Endoperoxide Synthases
650 0 4 _aSulfones
700 1 _aLaine, L
700 1 _aReicin, A
700 1 _aShapiro, D
700 1 _aBurgos-Vargas, R
700 1 _aDavis, B
700 1 _aDay, R
700 1 _aFerraz, M B
700 1 _aHawkey, C J
700 1 _aHochberg, M C
700 1 _aKvien, T K
700 1 _aSchnitzer, T J
773 0 _tThe New England journal of medicine
_gvol. 343
_gno. 21
_gp. 1520-8, 2 p following 1528
856 4 0 _uhttps://doi.org/10.1056/NEJM200011233432103
_zAvailable from publisher's website
999 _c11029499
_d11029499