000 02828 a2200805 4500
005 20250513223346.0
264 0 _c20001213
008 200012s 0 0 eng d
022 _a1061-4036
024 7 _a10.1038/81583
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJacobs, J J
245 0 0 _aSenescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.
_h[electronic resource]
260 _bNature genetics
_cNov 2000
300 _a291-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAdenocarcinoma
_xgenetics
650 0 4 _aAnimals
650 0 4 _aBreast Neoplasms
_xgenetics
650 0 4 _aCOS Cells
650 0 4 _aCarrier Proteins
_xgenetics
650 0 4 _aCell Cycle Proteins
_xgenetics
650 0 4 _aCell Transformation, Neoplastic
_xgenetics
650 0 4 _aCells, Cultured
650 0 4 _aCellular Senescence
_xgenetics
650 0 4 _aChromosomes, Human, Pair 17
_xgenetics
650 0 4 _aCyclin-Dependent Kinase Inhibitor p16
650 0 4 _aDNA-Binding Proteins
650 0 4 _aE2F Transcription Factors
650 0 4 _aE2F1 Transcription Factor
650 0 4 _aFemale
650 0 4 _aFibroblasts
_xcytology
650 0 4 _aGene Amplification
650 0 4 _aGene Deletion
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aGenes, BRCA1
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aNeoplasm Proteins
_xbiosynthesis
650 0 4 _aNeoplastic Syndromes, Hereditary
_xgenetics
650 0 4 _aNuclear Proteins
_xgenetics
650 0 4 _aOncogenes
650 0 4 _aPolycomb Repressive Complex 1
650 0 4 _aPromoter Regions, Genetic
650 0 4 _aProtein Biosynthesis
650 0 4 _aProteins
_xgenetics
650 0 4 _aProto-Oncogene Proteins
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-myc
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins p21(ras)
_xantagonists & inhibitors
650 0 4 _aRepressor Proteins
_xgenetics
650 0 4 _aRetinoblastoma-Binding Protein 1
650 0 4 _aT-Box Domain Proteins
_xgenetics
650 0 4 _aTranscription Factor DP1
650 0 4 _aTranscription Factors
_xantagonists & inhibitors
650 0 4 _aTransfection
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Protein p14ARF
700 1 _aKeblusek, P
700 1 _aRobanus-Maandag, E
700 1 _aKristel, P
700 1 _aLingbeek, M
700 1 _aNederlof, P M
700 1 _avan Welsem, T
700 1 _avan de Vijver, M J
700 1 _aKoh, E Y
700 1 _aDaley, G Q
700 1 _avan Lohuizen, M
773 0 _tNature genetics
_gvol. 26
_gno. 3
_gp. 291-9
856 4 0 _uhttps://doi.org/10.1038/81583
_zAvailable from publisher's website
999 _c11004992
_d11004992