000 01864 a2200505 4500
005 20250513220739.0
264 0 _c20000928
008 200009s 0 0 eng d
022 _a0006-2960
024 7 _a10.1021/bi000788y
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWeiss, K K
245 0 0 _aMolecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions.
_h[electronic resource]
260 _bBiochemistry
_cSep 2000
300 _a10684-94 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAmino Acid Substitution
_xgenetics
650 0 4 _aAnti-HIV Agents
_xpharmacology
650 0 4 _aBase Pair Mismatch
650 0 4 _aBinding Sites
_xgenetics
650 0 4 _aDNA Mutational Analysis
650 0 4 _aDNA Primers
_xchemistry
650 0 4 _aDideoxynucleotides
650 0 4 _aGlutamine
_xgenetics
650 0 4 _aGlycine
_xgenetics
650 0 4 _aHIV Reverse Transcriptase
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aLac Operon
650 0 4 _aLysine
_xgenetics
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aProtein Processing, Post-Translational
_xgenetics
650 0 4 _aProtein Structure, Secondary
_xgenetics
650 0 4 _aRNA
_xchemistry
650 0 4 _aSubstrate Specificity
_xgenetics
650 0 4 _aTemplates, Genetic
650 0 4 _aThymine Nucleotides
_xpharmacology
650 0 4 _aTryptophan
_xgenetics
650 0 4 _aZidovudine
_xanalogs & derivatives
700 1 _aIsaacs, S J
700 1 _aTran, N H
700 1 _aAdman, E T
700 1 _aKim, B
773 0 _tBiochemistry
_gvol. 39
_gno. 35
_gp. 10684-94
856 4 0 _uhttps://doi.org/10.1021/bi000788y
_zAvailable from publisher's website
999 _c10925451
_d10925451