000 02174 a2200577 4500
005 20250513215221.0
264 0 _c20000919
008 200009s 0 0 eng d
022 _a0027-8424
024 7 _a10.1073/pnas.160115697
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFarzan, M
245 0 0 _aBACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cAug 2000
300 _a9712-7 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAlzheimer Disease
_xgenetics
650 0 4 _aAmino Acid Sequence
650 0 4 _aAmino Acid Substitution
_xgenetics
650 0 4 _aAmyloid Precursor Protein Secretases
650 0 4 _aAmyloid beta-Peptides
_xchemistry
650 0 4 _aAmyloid beta-Protein Precursor
_xchemistry
650 0 4 _aArginine
_xgenetics
650 0 4 _aAspartic Acid Endopeptidases
_xchemistry
650 0 4 _aBinding Sites
650 0 4 _aCell Line
650 0 4 _aCloning, Molecular
650 0 4 _aEndopeptidases
650 0 4 _aGene Expression Profiling
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutation, Missense
_xgenetics
650 0 4 _aNervous System
_xenzymology
650 0 4 _aNetherlands
650 0 4 _aPeptide Fragments
_xchemistry
650 0 4 _aPhenylalanine
_xmetabolism
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aRNA, Messenger
_xanalysis
650 0 4 _aRecombinant Fusion Proteins
_xchemistry
650 0 4 _aSequence Homology, Amino Acid
650 0 4 _aSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
650 0 4 _aSubstrate Specificity
650 0 4 _aSweden
700 1 _aSchnitzler, C E
700 1 _aVasilieva, N
700 1 _aLeung, D
700 1 _aChoe, H
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 97
_gno. 17
_gp. 9712-7
856 4 0 _uhttps://doi.org/10.1073/pnas.160115697
_zAvailable from publisher's website
999 _c10880878
_d10880878