000 01982 a2200541 4500
005 20250513214610.0
264 0 _c20000817
008 200008s 0 0 eng d
022 _a0077-8923
024 7 _a10.1111/j.1749-6632.2000.tb06637.x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBandyopadhyay, D
245 0 0 _aMelanin accumulation accelerates melanocyte senescence by a mechanism involving p16INK4a/CDK4/pRB and E2F1.
_h[electronic resource]
260 _bAnnals of the New York Academy of Sciences
_cJun 2000
300 _a71-84 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aCDC2-CDC28 Kinases
650 0 4 _aCarrier Proteins
_xmetabolism
650 0 4 _aCell Cycle
650 0 4 _aCell Cycle Proteins
650 0 4 _aCells, Cultured
650 0 4 _aCellular Senescence
_xphysiology
650 0 4 _aCyclin E
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase 2
650 0 4 _aCyclin-Dependent Kinase 4
650 0 4 _aCyclin-Dependent Kinase Inhibitor p16
650 0 4 _aCyclin-Dependent Kinases
_xmetabolism
650 0 4 _aDNA-Binding Proteins
650 0 4 _aDown-Regulation
650 0 4 _aE2F Transcription Factors
650 0 4 _aE2F1 Transcription Factor
650 0 4 _aEnzyme Activation
650 0 4 _aHumans
650 0 4 _aMelanins
_xmetabolism
650 0 4 _aMelanocytes
_xcytology
650 0 4 _aPhosphorylation
650 0 4 _aPigments, Biological
_xphysiology
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
650 0 4 _aRetinoblastoma Protein
_xmetabolism
650 0 4 _aRetinoblastoma-Binding Protein 1
650 0 4 _aThymidylate Synthase
_xmetabolism
650 0 4 _aTranscription Factor DP1
650 0 4 _aTranscription Factors
_xmetabolism
700 1 _aMedrano, E E
773 0 _tAnnals of the New York Academy of Sciences
_gvol. 908
_gp. 71-84
856 4 0 _uhttps://doi.org/10.1111/j.1749-6632.2000.tb06637.x
_zAvailable from publisher's website
999 _c10861744
_d10861744