000			01988 a2200637 4500
005			20250513214002.0
264		0	_c20000803
008			200008s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm990612y _2doi
040			_aNLM _beng _cNLM
100	1		_aBarrow, J C
245	0	0	_aIn vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJul 2000
300			_a2703-18 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAdrenergic alpha-Antagonists _xchemical synthesis
650	0	4	_aAnimals
650	0	4	_aBiological Availability
650	0	4	_aCaco-2 Cells
650	0	4	_aCrystallography, X-Ray
650	0	4	_aDogs
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aProstatic Hyperplasia _xdrug therapy
650	0	4	_aPyrimidinones _xchemical synthesis
650	0	4	_aRadioligand Assay
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aReceptors, Adrenergic, alpha-1 _xdrug effects
650	0	4	_aStructure-Activity Relationship
700	1		_aNantermet, P G
700	1		_aSelnick, H G
700	1		_aGlass, K L
700	1		_aRittle, K E
700	1		_aGilbert, K F
700	1		_aSteele, T G
700	1		_aHomnick, C F
700	1		_aFreidinger, R M
700	1		_aRansom, R W
700	1		_aKling, P
700	1		_aReiss, D
700	1		_aBroten, T P
700	1		_aSchorn, T W
700	1		_aChang, R S
700	1		_aO'Malley, S S
700	1		_aOlah, T V
700	1		_aEllis, J D
700	1		_aBarrish, A
700	1		_aKassahun, K
700	1		_aLeppert, P
700	1		_aNagarathnam, D
700	1		_aForray, C
773	0		_tJournal of medicinal chemistry _gvol. 43 _gno. 14 _gp. 2703-18
856	4	0	_uhttps://doi.org/10.1021/jm990612y _zAvailable from publisher's website
999			_c10843710 _d10843710