000 01394 a2200349 4500
005 20250513212803.0
264 0 _c20000713
008 200007s 0 0 eng d
022 _a0006-2952
024 7 _a10.1016/s0006-2952(00)00335-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLewis, D F
245 0 0 _aOn the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics: towards the prediction of human p450 substrate specificity and metabolism.
_h[electronic resource]
260 _bBiochemical pharmacology
_cAug 2000
300 _a293-306 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBinding Sites
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHumans
650 0 4 _aIsoenzymes
_xantagonists & inhibitors
650 0 4 _aMetabolic Clearance Rate
650 0 4 _aMicrosomes
_xenzymology
650 0 4 _aModels, Chemical
650 0 4 _aPharmaceutical Preparations
_xmetabolism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSubstrate Specificity
773 0 _tBiochemical pharmacology
_gvol. 60
_gno. 3
_gp. 293-306
856 4 0 _uhttps://doi.org/10.1016/s0006-2952(00)00335-x
_zAvailable from publisher's website
999 _c10807419
_d10807419