000			01312 a2200373 4500
005			20250513212228.0
264		0	_c20000803
008			200008s 0 0 eng d
022			_a0264-6021
040			_aNLM _beng _cNLM
100	1		_aOwen, M R
245	0	0	_aEvidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. _h[electronic resource]
260			_bThe Biochemical journal _cJun 2000
300			_a607-14 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aElectron Transport _xdrug effects
650	0	4	_aElectron Transport Complex I
650	0	4	_aGluconeogenesis _xdrug effects
650	0	4	_aHypoglycemic Agents _xpharmacology
650	0	4	_aLiver _xdrug effects
650	0	4	_aMale
650	0	4	_aMetformin _xpharmacology
650	0	4	_aMitochondria _xdrug effects
650	0	4	_aNADH, NADPH Oxidoreductases _xantagonists & inhibitors
650	0	4	_aRats
650	0	4	_aRats, Wistar
650	0	4	_aSignal Transduction
650	0	4	_aSubmitochondrial Particles _xenzymology
650	0	4	_aTumor Cells, Cultured
700	1		_aDoran, E
700	1		_aHalestrap, A P
773	0		_tThe Biochemical journal _gvol. 348 Pt 3 _gp. 607-14
999			_c10791358 _d10791358