000 02076 a2200529 4500
005 20250513211635.0
264 0 _c20000629
008 200006s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm0001121
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHoepping, A
245 0 0 _aNovel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMay 2000
300 _a2064-71 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aCarrier Proteins
_xantagonists & inhibitors
650 0 4 _aCorpus Striatum
_xultrastructure
650 0 4 _aCyclization
650 0 4 _aDopamine
_xmetabolism
650 0 4 _aDopamine Plasma Membrane Transport Proteins
650 0 4 _aHeterocyclic Compounds, 3-Ring
_xchemical synthesis
650 0 4 _aMembrane Glycoproteins
_xantagonists & inhibitors
650 0 4 _aMembrane Transport Proteins
650 0 4 _aMesencephalon
_xultrastructure
650 0 4 _aMolecular Conformation
650 0 4 _aNerve Tissue Proteins
650 0 4 _aNorepinephrine
_xmetabolism
650 0 4 _aNorepinephrine Plasma Membrane Transport Proteins
650 0 4 _aOccipital Lobe
_xultrastructure
650 0 4 _aParietal Lobe
_xultrastructure
650 0 4 _aRats
650 0 4 _aSerotonin
_xmetabolism
650 0 4 _aSerotonin Plasma Membrane Transport Proteins
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSymporters
650 0 4 _aSynaptosomes
_xmetabolism
650 0 4 _aTritium
650 0 4 _aTropanes
_xchemistry
700 1 _aJohnson, K M
700 1 _aGeorge, C
700 1 _aFlippen-Anderson, J
700 1 _aKozikowski, A P
773 0 _tJournal of medicinal chemistry
_gvol. 43
_gno. 10
_gp. 2064-71
856 4 0 _uhttps://doi.org/10.1021/jm0001121
_zAvailable from publisher's website
999 _c10773352
_d10773352