000 | 01882 a2200541 4500 | ||
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005 | 20250513205558.0 | ||
264 | 0 | _c20000616 | |
008 | 200006s 0 0 eng d | ||
022 | _a0006-2960 | ||
024 | 7 |
_a10.1021/bi992372u _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aFowler, S M | |
245 | 0 | 0 |
_aAmino acid 305 determines catalytic center accessibility in CYP3A4. _h[electronic resource] |
260 |
_bBiochemistry _cApr 2000 |
||
300 |
_a4406-14 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAlanine _xgenetics |
650 | 0 | 4 |
_aAmino Acid Substitution _xgenetics |
650 | 0 | 4 | _aAryl Hydrocarbon Hydroxylases |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 |
_aCatalysis _xdrug effects |
650 | 0 | 4 |
_aClotrimazole _xpharmacology |
650 | 0 | 4 | _aCytochrome P-450 CYP3A |
650 | 0 | 4 | _aCytochrome P-450 Enzyme Inhibitors |
650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xchemistry |
650 | 0 | 4 |
_aDiazepam _xmetabolism |
650 | 0 | 4 |
_aEconazole _xpharmacology |
650 | 0 | 4 |
_aErythromycin _xmetabolism |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aImidazoles _xchemistry |
650 | 0 | 4 |
_aKetoconazole _xmetabolism |
650 | 0 | 4 | _aKinetics |
650 | 0 | 4 |
_aMiconazole _xpharmacology |
650 | 0 | 4 |
_aMixed Function Oxygenases _xantagonists & inhibitors |
650 | 0 | 4 |
_aMultienzyme Complexes _xantagonists & inhibitors |
650 | 0 | 4 |
_aMutation _xgenetics |
650 | 0 | 4 |
_aNifedipine _xmetabolism |
650 | 0 | 4 |
_aOxidoreductases, N-Demethylating _xantagonists & inhibitors |
650 | 0 | 4 | _aSubstrate Specificity |
650 | 0 | 4 |
_aTestosterone _xmetabolism |
700 | 1 | _aRiley, R J | |
700 | 1 | _aPritchard, M P | |
700 | 1 | _aSutcliffe, M J | |
700 | 1 | _aFriedberg, T | |
700 | 1 | _aWolf, C R | |
773 | 0 |
_tBiochemistry _gvol. 39 _gno. 15 _gp. 4406-14 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/bi992372u _zAvailable from publisher's website |
999 |
_c10711318 _d10711318 |