000 | 01548 a2200397 4500 | ||
---|---|---|---|
005 | 20250513205247.0 | ||
264 | 0 | _c20010301 | |
008 | 200103s 0 0 eng d | ||
022 | _a0264-6021 | ||
024 | 7 |
_a10.1042/0264-6021:3470519 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aXu-Welliver, M | |
245 | 0 | 0 |
_aPoint mutations at multiple sites including highly conserved amino acids maintain activity, but render O6-alkylguanine-DNA alkyltransferase insensitive to O6-benzylguanine. _h[electronic resource] |
260 |
_bThe Biochemical journal _cApr 2000 |
||
300 |
_a519-26 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. | ||
650 | 0 | 4 | _aAmino Acid Sequence |
650 | 0 | 4 |
_aAmino Acid Substitution _xgenetics |
650 | 0 | 4 |
_aAntineoplastic Agents _xpharmacology |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 |
_aConserved Sequence _xgenetics |
650 | 0 | 4 |
_aDNA Repair _xdrug effects |
650 | 0 | 4 |
_aDrug Resistance _xgenetics |
650 | 0 | 4 | _aEscherichia coli |
650 | 0 | 4 | _aGene Library |
650 | 0 | 4 |
_aGuanine _xanalogs & derivatives |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aMethylnitronitrosoguanidine _xpharmacology |
650 | 0 | 4 | _aMolecular Sequence Data |
650 | 0 | 4 |
_aO(6)-Methylguanine-DNA Methyltransferase _xchemistry |
650 | 0 | 4 |
_aPoint Mutation _xgenetics |
650 | 0 | 4 | _aSequence Alignment |
700 | 1 | _aPegg, A E | |
773 | 0 |
_tThe Biochemical journal _gvol. 347 _gno. Pt 2 _gp. 519-26 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1042/0264-6021:3470519 _zAvailable from publisher's website |
999 |
_c10703052 _d10703052 |