000 02083 a2200565 4500
005 20250513204203.0
264 0 _c20000425
008 200004s 0 0 eng d
022 _a0027-8424
024 7 _a10.1073/pnas.97.6.2785
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGambhir, S S
245 0 0 _aA mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cMar 2000
300 _a2785-90 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAcyclovir
_xmetabolism
650 0 4 _aAdenoviridae
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aAntiviral Agents
_xmetabolism
650 0 4 _aBlotting, Northern
650 0 4 _aBlotting, Western
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aEscherichia coli
_xmetabolism
650 0 4 _aFluorine
_xpharmacokinetics
650 0 4 _aGanciclovir
_xmetabolism
650 0 4 _aGenes, Reporter
650 0 4 _aHerpesvirus 1, Human
_xenzymology
650 0 4 _aLiver
_xmetabolism
650 0 4 _aMice
650 0 4 _aMutagenesis
650 0 4 _aProdrugs
_xmetabolism
650 0 4 _aRats
650 0 4 _aThymidine Kinase
_xgenetics
650 0 4 _aTime Factors
650 0 4 _aTomography, Emission-Computed
_xmethods
650 0 4 _aTransfection
650 0 4 _aTumor Cells, Cultured
700 1 _aBauer, E
700 1 _aBlack, M E
700 1 _aLiang, Q
700 1 _aKokoris, M S
700 1 _aBarrio, J R
700 1 _aIyer, M
700 1 _aNamavari, M
700 1 _aPhelps, M E
700 1 _aHerschman, H R
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 97
_gno. 6
_gp. 2785-90
856 4 0 _uhttps://doi.org/10.1073/pnas.97.6.2785
_zAvailable from publisher's website
999 _c10670889
_d10670889