000 01798 a2200505 4500
005 20250513204125.0
264 0 _c20000413
008 200004s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm9904607
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNacro, K
245 0 0 _aConformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMar 2000
300 _a921-44 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a4-Butyrolactone
_xanalogs & derivatives
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aBinding, Competitive
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDrug Design
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEnzyme Activation
650 0 4 _aEpidermal Growth Factor
_xantagonists & inhibitors
650 0 4 _aIsoenzymes
_xchemistry
650 0 4 _aLigands
650 0 4 _aModels, Molecular
650 0 4 _aProtein Kinase C
_xchemistry
650 0 4 _aProtein Kinase C-alpha
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Cells, Cultured
650 0 4 _aValerates
_xchemical synthesis
700 1 _aBienfait, B
700 1 _aLee, J
700 1 _aHan, K C
700 1 _aKang, J H
700 1 _aBenzaria, S
700 1 _aLewin, N E
700 1 _aBhattacharyya, D K
700 1 _aBlumberg, P M
700 1 _aMarquez, V E
773 0 _tJournal of medicinal chemistry
_gvol. 43
_gno. 5
_gp. 921-44
856 4 0 _uhttps://doi.org/10.1021/jm9904607
_zAvailable from publisher's website
999 _c10669066
_d10669066