000 | 01870 a2200565 4500 | ||
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005 | 20250513201532.0 | ||
264 | 0 | _c20000228 | |
008 | 200002s 0 0 eng d | ||
022 | _a0960-894X | ||
024 | 7 |
_a10.1016/s0960-894x(99)00573-9 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aPascal, Y | |
245 | 0 | 0 |
_aSynthesis and structure-activity relationships of 4-oxo-1-phenyl-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indoles: novel PDE4 inhibitors. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _cJan 2000 |
||
300 |
_a35-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_a3',5'-Cyclic-AMP Phosphodiesterases _xantagonists & inhibitors |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aBenzodiazepines _xchemical synthesis |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 | _aCyclic Nucleotide Phosphodiesterases, Type 4 |
650 | 0 | 4 | _aDogs |
650 | 0 | 4 | _aGuinea Pigs |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aIndoles _xchemical synthesis |
650 | 0 | 4 | _aInhibitory Concentration 50 |
650 | 0 | 4 |
_aPhosphodiesterase Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aRats, Inbred BN |
650 | 0 | 4 | _aRats, Wistar |
650 | 0 | 4 |
_aRolipram _xmetabolism |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _aSubstrate Specificity |
650 | 0 | 4 | _aU937 Cells |
700 | 1 | _aAndrianjara, C R | |
700 | 1 | _aAuclair, E | |
700 | 1 | _aAvenel, N | |
700 | 1 | _aBertin, B | |
700 | 1 | _aCalvet, A | |
700 | 1 | _aFéru, F | |
700 | 1 | _aLardon, S | |
700 | 1 | _aMoodley, I | |
700 | 1 | _aOuagued, M | |
700 | 1 | _aPayne, A | |
700 | 1 | _aPruniaux, M P | |
700 | 1 | _aSzilagyi, C | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 10 _gno. 1 _gp. 35-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/s0960-894x(99)00573-9 _zAvailable from publisher's website |
999 |
_c10591570 _d10591570 |