000 02360 a2200625 4500
005 20250513195826.0
264 0 _c20000111
008 200001s 0 0 eng d
022 _a0014-4827
024 7 _a10.1006/excr.1999.4688
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHaddad, M M
245 0 0 _aActivation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.
_h[electronic resource]
260 _bExperimental cell research
_cDec 1999
300 _a561-72 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aCarrier Proteins
650 0 4 _aCell Cycle Proteins
650 0 4 _aCells, Cultured
650 0 4 _aCellular Senescence
_xphysiology
650 0 4 _aCyclic AMP
_xphysiology
650 0 4 _aCyclin-Dependent Kinase 4
650 0 4 _aCyclin-Dependent Kinase Inhibitor p16
_xgenetics
650 0 4 _aCyclin-Dependent Kinase Inhibitor p27
650 0 4 _aCyclin-Dependent Kinases
_xmetabolism
650 0 4 _aDNA-Binding Proteins
650 0 4 _aE2F Transcription Factors
650 0 4 _aE2F1 Transcription Factor
650 0 4 _aE2F2 Transcription Factor
650 0 4 _aE2F4 Transcription Factor
650 0 4 _aGene Expression Regulation, Enzymologic
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aHumans
650 0 4 _aMelanins
_xbiosynthesis
650 0 4 _aMelanocytes
_xcytology
650 0 4 _aMelanoma
_xenzymology
650 0 4 _aMicrophthalmos
_xgenetics
650 0 4 _aMicrotubule-Associated Proteins
_xgenetics
650 0 4 _aPhosphorylation
650 0 4 _aProto-Oncogene Proteins
650 0 4 _aRetinoblastoma Protein
_xmetabolism
650 0 4 _aRetinoblastoma-Binding Protein 1
650 0 4 _aS Phase
_xphysiology
650 0 4 _aSignal Transduction
_xphysiology
650 0 4 _aSkin Neoplasms
_xenzymology
650 0 4 _aTranscription Factor DP1
650 0 4 _aTranscription Factors
_xgenetics
650 0 4 _aTumor Suppressor Proteins
700 1 _aXu, W
700 1 _aSchwahn, D J
700 1 _aLiao, F
700 1 _aMedrano, E E
773 0 _tExperimental cell research
_gvol. 253
_gno. 2
_gp. 561-72
856 4 0 _uhttps://doi.org/10.1006/excr.1999.4688
_zAvailable from publisher's website
999 _c10541458
_d10541458