000 01684 a2200421 4500
005 20250513194548.0
264 0 _c20000124
008 200001s 0 0 eng d
022 _a0764-4469
024 7 _a10.1016/s0764-4469(00)80037-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aArimondo, P B
245 0 0 _aTargeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin.
_h[electronic resource]
260 _bComptes rendus de l'Academie des sciences. Serie III, Sciences de la vie
_cSep 1999
300 _a785-90 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAminoglycosides
650 0 4 _aAnti-Bacterial Agents
_xchemistry
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aBase Sequence
650 0 4 _aCamptothecin
_xchemistry
650 0 4 _aDNA Topoisomerases, Type I
_xmetabolism
650 0 4 _aDrug Design
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHumans
650 0 4 _aMolecular Sequence Data
650 0 4 _aNucleic Acid Conformation
650 0 4 _aOligodeoxyribonucleotides
_xchemistry
650 0 4 _aSubstrate Specificity
650 0 4 _aTopoisomerase I Inhibitors
700 1 _aBailly, C
700 1 _aBoutorine, A
700 1 _aSun, J S
700 1 _aGarestier, T
700 1 _aHélène, C
773 0 _tComptes rendus de l'Academie des sciences. Serie III, Sciences de la vie
_gvol. 322
_gno. 9
_gp. 785-90
856 4 0 _uhttps://doi.org/10.1016/s0764-4469(00)80037-2
_zAvailable from publisher's website
999 _c10504402
_d10504402