000 01783 a2200481 4500
005 20250513194331.0
264 0 _c19991213
008 199912s 0 0 eng d
022 _a0021-9258
024 7 _a10.1074/jbc.274.45.32507
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRani, M R
245 0 0 _aCatalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cNov 1999
300 _a32507-11 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aCatalysis
650 0 4 _aDNA-Binding Proteins
_xmetabolism
650 0 4 _aEnzyme Activation
650 0 4 _aHumans
650 0 4 _aInterferon-beta
_xmetabolism
650 0 4 _aMembrane Proteins
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aProtein-Tyrosine Kinases
_xmetabolism
650 0 4 _aProteins
_xmetabolism
650 0 4 _aReceptor, Interferon alpha-beta
650 0 4 _aReceptors, Interferon
_xmetabolism
650 0 4 _aSTAT3 Transcription Factor
650 0 4 _aSignal Transduction
650 0 4 _aTYK2 Kinase
650 0 4 _aTrans-Activators
_xmetabolism
650 0 4 _aTumor Cells, Cultured
700 1 _aLeaman, D W
700 1 _aHan, Y
700 1 _aLeung, S
700 1 _aCroze, E
700 1 _aFish, E N
700 1 _aWolfman, A
700 1 _aRansohoff, R M
773 0 _tThe Journal of biological chemistry
_gvol. 274
_gno. 45
_gp. 32507-11
856 4 0 _uhttps://doi.org/10.1074/jbc.274.45.32507
_zAvailable from publisher's website
999 _c10499055
_d10499055