000 01511 a2200409 4500
005 20250513191035.0
264 0 _c19990902
008 199909s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm9902279
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBom, D
245 0 0 _aNovel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cAug 1999
300 _a3018-22 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aCamptothecin
_xanalogs & derivatives
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aDimyristoylphosphatidylcholine
_xchemistry
650 0 4 _aDrug Stability
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aFluorescence Polarization
650 0 4 _aHumans
650 0 4 _aHydrolysis
650 0 4 _aPhosphatidylglycerols
_xchemistry
650 0 4 _aSpectrometry, Fluorescence
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTopoisomerase I Inhibitors
700 1 _aCurran, D P
700 1 _aChavan, A J
700 1 _aKruszewski, S
700 1 _aZimmer, S G
700 1 _aFraley, K A
700 1 _aBurke, T G
773 0 _tJournal of medicinal chemistry
_gvol. 42
_gno. 16
_gp. 3018-22
856 4 0 _uhttps://doi.org/10.1021/jm9902279
_zAvailable from publisher's website
999 _c10405666
_d10405666