000 02171 a2200673 4500
005 20250513174716.0
264 0 _c19990520
008 199905s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm9801307
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJacobsen, E J
245 0 0 _aPiperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cApr 1999
300 _a1123-44 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAnti-Anxiety Agents
_xchemical synthesis
650 0 4 _aAnticonvulsants
_xchemical synthesis
650 0 4 _aAnxiety
_xmetabolism
650 0 4 _aBiological Availability
650 0 4 _aCell Line
650 0 4 _aCerebellum
_xdrug effects
650 0 4 _aConvulsants
_xtoxicity
650 0 4 _aCyclic GMP
_xantagonists & inhibitors
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aGABA Agonists
_xchemical synthesis
650 0 4 _aImidazoles
_xchemical synthesis
650 0 4 _aIn Vitro Techniques
650 0 4 _aLigands
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Conformation
650 0 4 _aPentylenetetrazole
_xtoxicity
650 0 4 _aPiperazines
_xchemical synthesis
650 0 4 _aQuinoxalines
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aRats, Inbred F344
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReceptors, GABA-A
_xmetabolism
650 0 4 _aSeizures
_xchemically induced
650 0 4 _aStructure-Activity Relationship
650 0 4 _aUrea
_xanalogs & derivatives
700 1 _aStelzer, L S
700 1 _aTenBrink, R E
700 1 _aBelonga, K L
700 1 _aCarter, D B
700 1 _aIm, H K
700 1 _aIm, W B
700 1 _aSethy, V H
700 1 _aTang, A H
700 1 _aVonVoigtlander, P F
700 1 _aPetke, J D
700 1 _aZhong, W Z
700 1 _aMickelson, J W
773 0 _tJournal of medicinal chemistry
_gvol. 42
_gno. 7
_gp. 1123-44
856 4 0 _uhttps://doi.org/10.1021/jm9801307
_zAvailable from publisher's website
999 _c10157353
_d10157353