000 02111 a2200529 4500
005 20250513170605.0
264 0 _c19990316
008 199903s 0 0 eng d
022 _a0732-183X
024 7 _a10.1200/JCO.1999.17.3.747
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHerben, V M
245 0 0 _aPhase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer.
_h[electronic resource]
260 _bJournal of clinical oncology : official journal of the American Society of Clinical Oncology
_cMar 1999
300 _a747-55 p.
_bdigital
500 _aPublication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xadverse effects
650 0 4 _aBlood Cell Count
650 0 4 _aCisplatin
_xadministration & dosage
650 0 4 _aFatigue
_xchemically induced
650 0 4 _aFemale
650 0 4 _aGranulocyte Colony-Stimulating Factor
_xadministration & dosage
650 0 4 _aHumans
650 0 4 _aInfusions, Intravenous
650 0 4 _aMiddle Aged
650 0 4 _aNausea
_xchemically induced
650 0 4 _aNeoplasm Staging
650 0 4 _aNeutropenia
_xchemically induced
650 0 4 _aOvarian Neoplasms
_xdrug therapy
650 0 4 _aPaclitaxel
_xadministration & dosage
650 0 4 _aThrombocytopenia
_xchemically induced
650 0 4 _aTopotecan
_xadministration & dosage
700 1 _aPanday, V R
700 1 _aRichel, D J
700 1 _aSchellens, J H
700 1 _avan der Vange, N
700 1 _aRosing, H
700 1 _aBeusenberg, F D
700 1 _aHearn, S
700 1 _aDoyle, E
700 1 _aBeijnen, J H
700 1 _aten Bokkel Huinink, W W
773 0 _tJournal of clinical oncology : official journal of the American Society of Clinical Oncology
_gvol. 17
_gno. 3
_gp. 747-55
856 4 0 _uhttps://doi.org/10.1200/JCO.1999.17.3.747
_zAvailable from publisher's website
999 _c10031256
_d10031256