Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines. [electronic resource]
Producer: 20060404Description: 1-10 p. digitalISSN:- 0041-008X
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Biological Transport
- Biotransformation
- Caco-2 Cells
- Carcinoma -- enzymology
- Carcinoma, Hepatocellular -- enzymology
- Cell Line, Tumor
- Colonic Neoplasms -- enzymology
- Cytochrome P-450 Enzyme System -- genetics
- Drug Screening Assays, Antitumor -- methods
- Female
- Humans
- Inactivation, Metabolic -- genetics
- Liver Neoplasms -- enzymology
- Membrane Transport Proteins -- genetics
- Ovarian Neoplasms -- enzymology
- Pharmacogenetics -- methods
- Polymorphism, Genetic
- Transferases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
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