Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of neurotrophic and inflammatory factors. [electronic resource]
Producer: 20190813Description: 302-312 p. digitalISSN:- 1878-1705
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Astrocytes -- drug effects
- Cells, Cultured
- Cerebellum -- pathology
- Disease Models, Animal
- Gene Expression Regulation
- Humans
- Inflammation Mediators -- metabolism
- Interleukin-6 -- genetics
- Lipopolysaccharides -- immunology
- NLR Family, Pyrin Domain-Containing 3 Protein -- metabolism
- Nerve Growth Factors -- metabolism
- Neurogenic Inflammation -- drug therapy
- Neuroprotection
- Nitric Oxide Synthase Type II -- genetics
- Pentacyclic Triterpenes -- pharmacology
- Rats
- Rats, Wistar
- Tubulin -- metabolism
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article
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