Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan. [electronic resource]
Producer: 20100407Description: 1700-10 p. digitalISSN:- 1538-7445
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Animals
- Antineoplastic Agents -- administration & dosage
- Carcinoma -- drug therapy
- Doxorubicin -- therapeutic use
- Drug Evaluation, Preclinical
- Drug Resistance, Neoplasm -- genetics
- Enzyme Inhibitors -- administration & dosage
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, BRCA1 -- physiology
- Genes, p53 -- physiology
- Mammary Neoplasms, Animal -- drug therapy
- Maximum Tolerated Dose
- Mice
- Mice, Knockout
- Phthalazines -- pharmacology
- Piperazines -- pharmacology
- Topoisomerase I Inhibitors
- Topotecan -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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