Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model. [electronic resource]
Producer: 20160707Description: 2180-92 p. digitalISSN:- 1569-8041
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Proliferation -- drug effects
- Disease Models, Animal
- Docetaxel
- Drug Therapy, Combination
- Female
- Flow Cytometry
- HeLa Cells
- Humans
- Immunoenzyme Techniques
- Mice
- Molecular Structure
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Survival Rate
- Taxoids -- pharmacology
- Triple Negative Breast Neoplasms -- drug therapy
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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