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Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics. [electronic resource] by
- Roumen, Luc
- Sanders, Marijn P A
- Pieterse, Koen
- Hilbers, Peter A J
- Plate, Ralf
- Custers, Erica
- de Gooyer, Marcel
- Smits, Jos F M
- Beugels, Ilona
- Emmen, Judith
- Ottenheijm, Harry C J
- Leysen, Dirk
- Hermans, J J R
Producer: 20071206
In:
Journal of computer-aided molecular design vol. 21
Availability: No items available.
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7.
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Complete inhibition of rhTSH-, Graves' disease IgG-, and M22-induced cAMP production in differentiated orbital fibroblasts by a low-molecular-weight TSHR antagonist. [electronic resource] by
- van Zeijl, Clementine J J
- van Koppen, Chris J
- Surovtseva, Olga V
- de Gooyer, Marcel E
- Plate, Ralf
- Conti, Paolo
- Karstens, Willem-Jan
- Timmers, Marco
- Saeed, Peerooz
- Wiersinga, Wilmar M
- Miltenburg, André M M
- Fliers, Eric
- Boelen, Anita
Producer: 20120723
In:
The Journal of clinical endocrinology and metabolism vol. 97
Availability: No items available.
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8.
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Application of a ligand-based theoretical approach to derive conversion paths and ligand conformations in CYP11B2-mediated aldosterone formation. [electronic resource] by
- Roumen, Luc
- Van Hoof, Bram
- Pieterse, Koen
- Hilbers, Peter A J
- Custers, Erica M G
- Plate, Ralf
- De Gooyer, Marcel
- Beugels, Ilona P E
- Emmen, Judith M A
- Leysen, Dirk
- Smits, Jos F M
- Ottenheijm, Harry C J
- Hermans, J J Rob
Producer: 20110923
In:
Journal of computational chemistry vol. 32
Availability: No items available.
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Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone. [electronic resource] by
- Minnaard-Huiban, Monica
- Emmen, Judith M A
- Roumen, Luc
- Beugels, Ilona P E
- Cohuet, Géraldine M S
- van Essen, Helma
- Ruijters, Eveline
- Pieterse, Koen
- Hilbers, Peter A J
- Ottenheijm, Harry C J
- Plate, Ralf
- de Gooyer, Marcel E
- Smits, Jos F M
- Hermans, J J Rob
Producer: 20080226
In:
Endocrinology vol. 149
Availability: No items available.
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10.
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Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). [electronic resource] by
- Roumen, Luc
- Peeters, Joris W
- Emmen, Judith M A
- Beugels, Ilona P E
- Custers, Erica M G
- de Gooyer, Marcel
- Plate, Ralf
- Pieterse, Koen
- Hilbers, Peter A J
- Smits, Jos F M
- Vekemans, Jef A J
- Leysen, Dirk
- Ottenheijm, Harry C J
- Janssen, Henk M
- Hermans, J J Rob
Producer: 20100323
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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11.
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Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor. [electronic resource] by
- van Koppen, Chris J
- de Gooyer, Marcel E
- Karstens, Willem-Jan
- Plate, Ralf
- Conti, Paolo G M
- van Achterberg, Tanja A E
- van Amstel, Monique G A
- Brands, Jolanda H G M
- Wat, Jesse
- Berg, Rob J W
- Lane, J Robert D
- Miltenburg, Andre M M
- Timmers, C Marco
Producer: 20120723
In:
British journal of pharmacology vol. 165
Availability: No items available.
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