Structural and stereoelectronic requirements for the inhibition of mammalian 2,3-oxidosqualene cyclase by substituted isoquinoline derivatives. [electronic resource]
Producer: 19960823Description: 2302-12 p. digitalISSN:- 0022-2623
- Animals
- Anticholesteremic Agents -- chemical synthesis
- Cholesterol -- biosynthesis
- Drug Design
- Enzyme Inhibitors -- chemical synthesis
- Intramolecular Transferases
- Isomerases -- antagonists & inhibitors
- Isoquinolines -- chemical synthesis
- Kinetics
- Microsomes, Liver -- enzymology
- Molecular Structure
- Protein Binding
- Rats
- Squalene -- analogs & derivatives
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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