Administration of granulocyte colony-stimulating factor induces immunomodulation, recruitment of T regulatory cells, reduction of myocarditis and decrease of parasite load in a mouse model of chronic Chagas disease cardiomyopathy. [electronic resource]
Producer: 20140204Description: 4691-702 p. digitalISSN:- 1530-6860
- Animals
- CD3 Complex -- genetics
- Chagas Cardiomyopathy -- drug therapy
- Cytokines -- genetics
- Fibrosis -- drug therapy
- Forkhead Transcription Factors -- genetics
- Galectin 3 -- genetics
- Granulocyte Colony-Stimulating Factor -- administration & dosage
- Heart -- parasitology
- Humans
- Immunomodulation
- Injections, Intraperitoneal
- Intercellular Adhesion Molecule-1 -- genetics
- Mice
- Mice, Inbred C57BL
- Myocarditis -- drug therapy
- Myocardium -- immunology
- Parasite Load
- Syndecan-4 -- genetics
- T-Lymphocytes, Regulatory -- drug effects
- Transcription, Genetic
- Trypanosoma cruzi -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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