The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development. [electronic resource]
Producer: 20090112Description: 19932-7 p. digitalISSN:- 1091-6490
- Adenocarcinoma -- chemically induced
- Animals
- Cell Line, Tumor
- Chromosomes, Human, Pair 3 -- genetics
- DNA Methylation
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Genes, Tumor Suppressor
- Genes, ras
- Genetic Predisposition to Disease
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- LIM Domain Proteins
- Loss of Heterozygosity
- Lung Neoplasms -- chemically induced
- Mice
- Mice, Mutant Strains
- Promoter Regions, Genetic
- Pulmonary Alveoli -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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