Neuroblastoma cells transiently transfected to simultaneously express the co-stimulatory molecules CD54, CD80, CD86, and CD137L generate antitumor immunity in mice. [electronic resource]
Producer: 20051207Description: 449-60 p. digitalISSN:- 1524-9557
- Animals
- Antigens, CD -- biosynthesis
- Antineoplastic Agents -- pharmacology
- B7-1 Antigen -- biosynthesis
- Cancer Vaccines -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- Electroporation
- Flow Cytometry
- Genetic Vectors
- Humans
- In Vitro Techniques
- Intercellular Adhesion Molecule-1 -- biosynthesis
- Interferon-gamma -- metabolism
- Mice
- Mice, Inbred C57BL
- Microscopy, Confocal
- Neuroblastoma -- metabolism
- Plasmids -- metabolism
- Receptors, Nerve Growth Factor -- biosynthesis
- Receptors, Tumor Necrosis Factor -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction
- Spleen -- cytology
- T-Lymphocytes -- metabolism
- Time Factors
- Transcription, Genetic
- Transfection
- Tumor Necrosis Factor Receptor Superfamily, Member 9
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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