PA-457: a potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing. [electronic resource]
Producer: 20040105Description: 13555-60 p. digitalISSN:- 0027-8424
- Anti-HIV Agents -- pharmacology
- Binding Sites
- Chromobox Protein Homolog 5
- Drug Design
- Gene Products, gag -- antagonists & inhibitors
- Genotype
- HIV Core Protein p24 -- metabolism
- HeLa Cells
- Humans
- Inhibitory Concentration 50
- Microscopy, Electron
- Models, Chemical
- Models, Genetic
- Mutation
- Plasmids -- metabolism
- Precipitin Tests
- Succinates -- chemistry
- Triterpenes -- chemistry
- gag Gene Products, Human Immunodeficiency Virus
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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