Depletion of WRN enhances DNA damage in HeLa cells exposed to the benzene metabolite, hydroquinone. [electronic resource]
Producer: 20080530Description: 54-61 p. digitalISSN:- 0027-5107
- Apoptosis -- drug effects
- Benzene -- metabolism
- Blotting, Western
- Cell Proliferation -- drug effects
- Comet Assay
- DNA Breaks, Double-Stranded -- drug effects
- DNA Damage
- DNA Repair
- Exodeoxyribonucleases -- genetics
- Flow Cytometry
- HeLa Cells
- Histones -- metabolism
- Humans
- Hydroquinones -- metabolism
- RNA Interference
- RNA, Small Interfering -- genetics
- RecQ Helicases -- genetics
- Transfection
- Tumor Suppressor Protein p53 -- metabolism
- Werner Syndrome Helicase
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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