Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions. [electronic resource]
Producer: 20121120Description: 170-8 p. digitalISSN:- 1424-3911
- Adenocarcinoma -- drug therapy
- Adult
- Aged
- Animals
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Cobalt -- pharmacology
- Drug Screening Assays, Antitumor
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Lymph Nodes -- pathology
- Lymphatic Metastasis
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Neoplasm Staging
- Oxidative Stress
- Oxygen -- administration & dosage
- Pancreatic Neoplasms -- drug therapy
- RNA, Small Interfering -- genetics
- Toll-Like Receptor 4 -- genetics
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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