Sorafenib metabolism is significantly altered in the liver tumor tissue of hepatocellular carcinoma patient. [electronic resource]
Producer: 20150129Description: e96664 p. digitalISSN:- 1932-6203
- Adult
- Aged
- Antineoplastic Agents -- pharmacokinetics
- Carcinoma, Hepatocellular -- drug therapy
- Cytochrome P-450 CYP3A -- metabolism
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Glucuronosyltransferase -- metabolism
- Humans
- Liver -- drug effects
- Liver Neoplasms -- drug therapy
- Male
- Microsomes, Liver -- drug effects
- Middle Aged
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds -- pharmacokinetics
- Reproducibility of Results
- Sorafenib
- UDP-Glucuronosyltransferase 1A9
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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