Tenacigenin B ester derivatives from Marsdenia tenacissima actively inhibited CYP3A4 and enhanced in vivo antitumor activity of paclitaxel. [electronic resource]
Producer: 20190424Description: 309-319 p. digitalISSN:- 1872-7573
- Animals
- Antineoplastic Agents, Phytogenic -- administration & dosage
- Cytochrome P-450 CYP3A -- drug effects
- Drug Synergism
- Esters -- chemistry
- Female
- HeLa Cells
- Humans
- Marsdenia -- chemistry
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Microsomes, Liver -- drug effects
- Molecular Docking Simulation
- Paclitaxel -- administration & dosage
- Rats
- Rats, Sprague-Dawley
- Steroids -- chemistry
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article
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