Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo. [electronic resource]
Producer: 20051221Description: 6002-11 p. digitalISSN:- 1078-0432
- Animals
- Antineoplastic Agents -- chemistry
- Apoptosis -- drug effects
- Binding Sites
- Binding, Competitive -- drug effects
- Blotting, Western
- Cell Cycle Proteins -- metabolism
- Cell Division -- drug effects
- Cell Line
- Cell Line, Tumor
- Cell Survival -- drug effects
- Colchicine -- pharmacology
- Diterpenes -- chemistry
- Dose-Response Relationship, Drug
- Drug Resistance, Multiple -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Drugs, Chinese Herbal
- G2 Phase -- drug effects
- HeLa Cells
- Humans
- Liver Neoplasms -- drug therapy
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Microscopy, Fluorescence
- Microtubules -- metabolism
- Molecular Structure
- Time Factors
- Treatment Outcome
- Tubulin -- metabolism
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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