Topotecan induces apoptosis via ASCT2 mediated oxidative stress in gastric cancer. [electronic resource]
Producer: 20190715Description: 117-128 p. digitalISSN:- 1618-095X
- Amino Acid Transport System ASC -- genetics
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Down-Regulation -- drug effects
- Female
- Gene Expression Regulation, Neoplastic
- Glutamine -- metabolism
- Glutathione -- metabolism
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mice, Inbred BALB C
- Minor Histocompatibility Antigens -- genetics
- Mitochondria -- drug effects
- Molecular Targeted Therapy -- methods
- Oxidative Stress -- drug effects
- Stomach Neoplasms -- drug therapy
- Topotecan -- pharmacology
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Publication Type: Journal Article
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