Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. [electronic resource]
Producer: 20200817Description: 941-955.e20 p. digitalISSN:- 1097-4172
- Animals
- Caspase 1 -- chemistry
- Caspases, Initiator -- chemistry
- Crystallography, X-Ray
- HEK293 Cells
- HeLa Cells
- Humans
- Hydrophobic and Hydrophilic Interactions
- Inflammasomes -- genetics
- Intracellular Signaling Peptides and Proteins -- chemistry
- Multiprotein Complexes -- chemistry
- Phosphate-Binding Proteins -- chemistry
- Protein Conformation, beta-Strand -- genetics
- Protein Domains -- genetics
- Protein Processing, Post-Translational -- genetics
- Proteolysis
- Pyroptosis -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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