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Methylenedioxy- and ethylenedioxy-fused indolocarbazoles: potent human topoisomerase I inhibitors and antitumor agents. [electronic resource] by
- Zembower, David E
- Xie, Yongping
- Koohang, Ali
- Kuffel, Mary J
- Ames, Matthew M
- Zhou, Yasheen
- Mishra, Rama
- Mar, Aye Aye
- Flavin, Michael T
- Xu, Ze-Qi
Producer: 20130514
In:
Anti-cancer agents in medicinal chemistry vol. 12
Availability: No items available.
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Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 receptor antagonist, as a novel antiplatelet agent that does not prolong bleeding. [electronic resource] by
- Singh, Jasbir
- Zeller, Wayne
- Zhou, Nian
- Hategan, Georgeta
- Mishra, Rama K
- Polozov, Alex
- Yu, Peng
- Onua, Emmanuel
- Zhang, Jun
- Ramírez, José L
- Sigthorsson, Gudmundur
- Thorsteinnsdottir, Margret
- Kiselyov, Alex S
- Zembower, David E
- Andrésson, Thorkell
- Gurney, Mark E
Producer: 20100202
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. [electronic resource] by
- Davies, Douglas R
- Mamat, Bjorn
- Magnusson, Olafur T
- Christensen, Jeff
- Haraldsson, Magnus H
- Mishra, Rama
- Pease, Brian
- Hansen, Erik
- Singh, Jasbir
- Zembower, David
- Kim, Hidong
- Kiselyov, Alex S
- Burgin, Alex B
- Gurney, Mark E
- Stewart, Lance J
Producer: 20090921
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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Antagonists of the EP3 receptor for prostaglandin E2 are novel antiplatelet agents that do not prolong bleeding. [electronic resource] by
- Singh, Jasbir
- Zeller, Wayne
- Zhou, Nian
- Hategen, Georgeta
- Mishra, Rama
- Polozov, Alex
- Yu, Peng
- Onua, Emmanuel
- Zhang, Jun
- Zembower, David
- Kiselyov, Alex
- Ramírez, José L
- Sigthorsson, Gudmundur
- Bjornsson, Jon Mar
- Thorsteinsdottir, Margret
- Andrésson, Thorkell
- Bjarnadottir, Maria
- Magnusson, Olafur
- Fabre, Jean-Etienne
- Stefansson, Kari
- Gurney, Mark E
Producer: 20100825
In:
ACS chemical biology vol. 4
Availability: No items available.
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Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis. [electronic resource] by
- Sandanayaka, Vincent
- Mamat, Bjorn
- Mishra, Rama K
- Winger, Jennifer
- Krohn, Michael
- Zhou, Li-Ming
- Keyvan, Monica
- Enache, Livia
- Sullins, David
- Onua, Emmanuel
- Zhang, Jun
- Halldorsdottir, Gudrun
- Sigthorsdottir, Heida
- Thorlaksdottir, Audur
- Sigthorsson, Gudmundur
- Thorsteinnsdottir, Margret
- Davies, Douglas R
- Stewart, Lance J
- Zembower, David E
- Andresson, Thorkell
- Kiselyov, Alex S
- Singh, Jasbir
- Gurney, Mark E
Producer: 20100302
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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