Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. [electronic resource]
Producer: 20151207Description: 4821-33 p. digitalISSN:- 1476-5594
- Animals
- Breast Neoplasms -- genetics
- Cell Transformation, Neoplastic -- genetics
- Female
- Fibroblasts -- drug effects
- Humans
- Kruppel-Like Transcription Factors -- genetics
- MCF-7 Cells
- Mesenchymal Stem Cells -- metabolism
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Neoplastic Stem Cells -- drug effects
- Osteopontin -- pharmacology
- Signal Transduction -- drug effects
- Transforming Growth Factor beta1 -- genetics
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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