Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF). [electronic resource]
Producer: 20201023Description: 2905 p. digitalISSN:- 2045-2322
- Aged
- Animals
- Antineoplastic Agents -- therapeutic use
- Brain Neoplasms -- drug therapy
- Cell Line, Tumor
- DNA Methylation
- DNA Modification Methylases -- genetics
- DNA Repair Enzymes -- genetics
- Drug Resistance, Neoplasm
- Drug Therapy, Combination
- Female
- Glioblastoma -- drug therapy
- Humans
- Macrophage Migration-Inhibitory Factors -- metabolism
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Proteome
- Pyridines -- therapeutic use
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Survival Analysis
- Temozolomide -- therapeutic use
- Tumor Suppressor Proteins -- genetics
- Up-Regulation
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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