Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo. [electronic resource]
Producer: 20170313Description: 690-694 p. digitalISSN:- 1872-7913
- Animals
- Antiprotozoal Agents -- pharmacology
- Auranofin -- pharmacology
- Cell Survival -- drug effects
- Disease Models, Animal
- Drug Repositioning
- Enzyme Inhibitors -- pharmacology
- Female
- Inhibitory Concentration 50
- Mice, Inbred C57BL
- Thioredoxin-Disulfide Reductase -- antagonists & inhibitors
- Treatment Outcome
- Trichomonas Vaginitis -- drug therapy
- Trichomonas vaginalis -- drug effects
- Tritrichomonas foetus -- drug effects
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Publication Type: Journal Article
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