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	1.	Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation. [electronic resource] by Kawada, Hatsuo Ebiike, Hirosato Tsukazaki, Masao Nakamura, Mitsuaki Morikami, Kenji Yoshinari, Kiyoshi Yoshida, Miyuki Ogawa, Kotaro Shimma, Nobuo Tsukuda, Takuo Ohwada, Jun Producer: 20130625 In: Bioorganic & medicinal chemistry letters vol. 23 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	2.	Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability. [electronic resource] by Kawada, Hatsuo Ebiike, Hirosato Tsukazaki, Masao Yamamoto, Shun Koyama, Kohei Nakamura, Mitsuaki Morikami, Kenji Yoshinari, Kiyoshi Yoshida, Miyuki Ogawa, Kotaro Shinma, Nobuo Tsukuda, Takuo Ohwada, Jun Producer: 20161012 In: Bioorganic & medicinal chemistry vol. 23 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	3.	Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents. [electronic resource] by Kawada, Hatsuo Ebiike, Hirosato Tsukazaki, Masao Yamamoto, Shun Koyama, Kohei Nakamura, Mitsuaki Morikami, Kenji Yoshinari, Kiyoshi Yoshida, Miyuki Ogawa, Kotaro Shimma, Nobuo Tsukuda, Takuo Ohwada, Jun Producer: 20171023 In: Bioorganic & medicinal chemistry vol. 24 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	4.	Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799. [electronic resource] by Ohwada, Jun Ebiike, Hirosato Kawada, Hatsuo Tsukazaki, Masao Nakamura, Mitsuaki Miyazaki, Takuya Morikami, Kenji Yoshinari, Kiyoshi Yoshida, Miyuki Kondoh, Osamu Kuramoto, Shino Ogawa, Kotaro Aoki, Yuko Shimma, Nobuo Producer: 20110705 In: Bioorganic & medicinal chemistry letters vol. 21 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	5.	Design and synthesis of novel prodrugs of 2'-deoxy-2'-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues. [electronic resource] by Kohchi, Yasunori Hattori, Kazuo Oikawa, Nobuhiro Mizuguchi, Eisaku Isshiki, Yoshiaki Aso, Kohsuke Yoshinari, Kiyoshi Shirai, Haruyoshi Miwa, Masanori Inagaki, Yukiko Ura, Masako Ogawa, Kotaroh Okabe, Hisafumi Ishitsuka, Hideo Shimma, Nobuo Producer: 20070530 In: Bioorganic & medicinal chemistry letters vol. 17 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	6.	The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitors. [electronic resource] by Aoki, Toshihiro Hyohdoh, Ikumi Furuichi, Noriyuki Ozawa, Sawako Watanabe, Fumio Matsushita, Masayuki Sakaitani, Masahiro Ori, Kazutomo Takanashi, Kenji Harada, Naoki Tomii, Yasushi Tabo, Mitsuyasu Yoshinari, Kiyoshi Aoki, Yuko Shimma, Nobuo Iikura, Hitoshi Producer: 20140817 In: Bioorganic & medicinal chemistry letters vol. 23 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	7.	Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning. [electronic resource] by Aoki, Toshihiro Hyohdoh, Ikumi Furuichi, Noriyuki Ozawa, Sawako Watanabe, Fumio Matsushita, Masayuki Sakaitani, Masahiro Morikami, Kenji Takanashi, Kenji Harada, Naoki Tomii, Yasushi Shiraki, Koji Furumoto, Kentaro Tabo, Mitsuyasu Yoshinari, Kiyoshi Ori, Kazutomo Aoki, Yuko Shimma, Nobuo Iikura, Hitoshi Producer: 20140606 In: ACS medicinal chemistry letters vol. 5 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	8.	Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties. [electronic resource] by Hyohdoh, Ikumi Furuichi, Noriyuki Aoki, Toshihiro Itezono, Yoshiko Shirai, Haruyoshi Ozawa, Sawako Watanabe, Fumio Matsushita, Masayuki Sakaitani, Masahiro Ho, Pil-Su Takanashi, Kenji Harada, Naoki Tomii, Yasushi Yoshinari, Kiyoshi Ori, Kazutomo Tabo, Mitsuyasu Aoki, Yuko Shimma, Nobuo Iikura, Hitoshi Producer: 20140605 In: ACS medicinal chemistry letters vol. 4 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	9.	Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog. [electronic resource] by Ohwada, Jun Ozawa, Sawako Kohchi, Masami Fukuda, Hiroshi Murasaki, Chikako Suda, Hitomi Murata, Takeshi Niizuma, Satoshi Tsukazaki, Masao Ori, Kazutomo Yoshinari, Kiyoshi Itezono, Yoshiko Endo, Mika Ura, Masako Tanimura, Hiromi Miyazaki, Yoko Kawashima, Akira Nagao, Shunsuke Namba, Eitarou Ogawa, Koutarou Kobayashi, Kazuko Okabe, Hisafumi Umeda, Isao Shimma, Nobuo Producer: 20090629 In: Bioorganic & medicinal chemistry letters vol. 19 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	10.	Synthesis of new camptothecin analogs with improved antitumor activities. [electronic resource] by Niizuma, Satoshi Tsukazaki, Masao Suda, Hitomi Murata, Takeshi Ohwada, Jun Ozawa, Sawako Fukuda, Hiroshi Murasaki, Chikako Kohchi, Masami Morikami, Kenji Yoshinari, Kiyoshi Endo, Mika Ura, Masako Tanimura, Hiromi Miyazaki, Yoko Takasuka, Tsuyoshi Kawashima, Akira Nanba, Eitaro Nakano, Kounosuke Ogawa, Kotaro Kobayashi, Kazuko Okabe, Hisafumi Umeda, Isao Shimma, Nobuo Producer: 20090615 In: Bioorganic & medicinal chemistry letters vol. 19 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)