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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs). [electronic resource] by
- Reid, Emily E
- Archer, Katie E
- Shizuka, Manami
- McShea, Molly A
- Maloney, Erin K
- Ab, Olga
- Lanieri, Leanne
- Wilhelm, Alan
- Ponte, Jose F
- Yoder, Nicholas C
- Chari, Ravi V J
- Miller, Michael L
Producer: 20200915
In:
Bioorganic & medicinal chemistry letters vol. 29
Availability: No items available.
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14.
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Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation. [electronic resource] by
- Bai, Chen
- Reid, Emily E
- Wilhelm, Alan
- Shizuka, Manami
- Maloney, Erin K
- Laleau, Rassol
- Harvey, Lauren
- Archer, Katie E
- Vitharana, Dilrukshi
- Adams, Sharlene
- Kovtun, Yelena
- Miller, Michael L
- Chari, Ravi
- Keating, Thomas A
- Yoder, Nicholas C
Producer: 20210204
In:
Bioconjugate chemistry vol. 31
Availability: No items available.
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15.
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Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid Conjugates. [electronic resource] by
- Ponte, Jose F
- Sun, Xiuxia
- Yoder, Nicholas C
- Fishkin, Nathan
- Laleau, Rassol
- Coccia, Jennifer
- Lanieri, Leanne
- Bogalhas, Megan
- Wang, Lintao
- Wilhelm, Sharon
- Widdison, Wayne
- Pinkas, Jan
- Keating, Thomas A
- Chari, Ravi
- Erickson, Hans K
- Lambert, John M
Producer: 20170612
In:
Bioconjugate chemistry vol. 27
Availability: No items available.
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16.
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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates. [electronic resource] by
- Catcott, Kalli C
- McShea, Molly A
- Bialucha, Carl Uli
- Miller, Kathy L
- Hicks, Stuart W
- Saxena, Parmita
- Gesner, Thomas G
- Woldegiorgis, Mikias
- Lewis, Megan E
- Bai, Chen
- Fleming, Michael S
- Ettenberg, Seth A
- Erickson, Hans K
- Yoder, Nicholas C
Producer: 20161213
In:
mAbs vol. 8
Availability: No items available.
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17.
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A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation. [electronic resource] by
- Yoder, Nicholas C
- Bai, Chen
- Tavares, Daniel
- Widdison, Wayne C
- Whiteman, Kathleen R
- Wilhelm, Alan
- Wilhelm, Sharon D
- McShea, Molly A
- Maloney, Erin K
- Ab, Olga
- Wang, Lintao
- Jin, Shan
- Erickson, Hans K
- Keating, Thomas A
- Lambert, John M
Producer: 20200608
In:
Molecular pharmaceutics vol. 16
Availability: No items available.
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18.
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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells. [electronic resource] by
- Kovtun, Yelena
- Jones, Gregory E
- Adams, Sharlene
- Harvey, Lauren
- Audette, Charlene A
- Wilhelm, Alan
- Bai, Chen
- Rui, Lingyun
- Laleau, Rassol
- Liu, Fenghua
- Ab, Olga
- Setiady, Yulius
- Yoder, Nicholas C
- Goldmacher, Victor S
- Chari, Ravi V J
- Pinkas, Jan
- Chittenden, Thomas
Producer: 20190308
In:
Blood advances vol. 2
Availability: No items available.
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19.
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Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs). [electronic resource] by
- Reid, Emily E
- Archer, Katie E
- Shizuka, Manami
- Wilhelm, Alan
- Yoder, Nicholas C
- Bai, Chen
- Fishkin, Nathan E
- Harris, Luke
- Maloney, Erin K
- Salomon, Paulin
- Hong, Erica
- Wu, Rui
- Ab, Olga
- Jin, Shan
- Lai, Katharine C
- Sikka, Surina
- Chari, Ravi V J
- Miller, Michael L
Publication details: ACS medicinal chemistry letters Aug 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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20.
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Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates. [electronic resource] by
- Sun, Xiuxia
- Ponte, Jose F
- Yoder, Nicholas C
- Laleau, Rassol
- Coccia, Jennifer
- Lanieri, Leanne
- Qiu, Qifeng
- Wu, Rui
- Hong, Erica
- Bogalhas, Megan
- Wang, Lintao
- Dong, Ling
- Setiady, Yulius
- Maloney, Erin K
- Ab, Olga
- Zhang, Xiaoyan
- Pinkas, Jan
- Keating, Thomas A
- Chari, Ravi
- Erickson, Hans K
- Lambert, John M
Producer: 20170817
In:
Bioconjugate chemistry vol. 28
Availability: No items available.
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